Lobular carcinoma in situ (LCIS) is a non-invasive multicentric proliferation of atypical epithelial cells in the lobules and terminal ducts of the breast.
Atypical ductal hyperplasia (ADH) is a proliferation of ductal epithelial cells in which some, but not all, features of DCIS are present.
Atypical lobular hyperplasia (ALH) describes cells similar to those seen in LCIS that only partially occlude the duct lumen and slightly distend the lobule.
National Breast and Ovarian Cancer Centre’s guide The clinical management of ductal carcinoma in situ, lobular carcinoma in situ and atypical hyperplasia of the breast is designed to assist in decision making by women and their doctors.
Clinical resources
- The clinical management of ductal carcinoma in situ, lobular carcinoma in situ and atypical hyperplasia of the breast
Publication date: 2003
Endorsed by The Royal Australasian College of Surgeons, The Royal College of Pathologists of Australasia, The Royal Australian and New Zealand College of Radiologists, The Cancer Council Australia and Breast Cancer Network Australia.



